综合医院抑郁障碍的临床特点和治疗
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资料包括： 论文(3页2302字)
说明：
【摘 要】 目的：探讨综合性医院抑郁障碍的临 床特点及治疗。方法：将各科以躯体不适就诊但经多方查治无效而转 来心理门诊的患者，进行汉密尔顿抑郁量表(HAMD)测评，HAMD≥18分者入组共70例，分别给 每日氟西汀20mg治疗6周，治疗前后查HAMD，并进行疗效评定。结果：70例 中，轻度、中度抑郁占85.7%，重度抑郁占14.3%。有71.49%的初诊患者的第一主诉是睡 眠 障碍和躯体不适。经服用抗抑郁剂氟西汀治疗六周后，HAMD评分结果明显下降(P＜0.01)， 痊愈率68.9%，显效率27.8%，进步1.64%，无效1.64%。治疗前后HAMD量表的五项因子评 分均有明显下降，具有显著意义(P＜0.01)。结论：综合医院抑郁障 碍患者及时识别、诊断，适当应用抗抑郁剂可有效缓解抑郁症状和躯体症状，减少不必要的 检查和治疗，利于患者疾病的康复。
关键词： 抑郁障碍,临床特点,抗抑郁治疗
Depression, Corresponding Treatment and Outcome in General Hos pital
【Abstract】Objective: To study depression, corresponding treatm ent and outcome in general hospital. Method: All patients referr ed to clinic of psychological co unsel were screened by HAMD, 70 of them scored higher than 18 were included. An t itdepressant (Flucidine 20 mg per day) was given for 6 weeks. Results: Among 70 p atients with depression, 71.5% consulted their physician with chief complaint of sleep disorder or somatic discomfort first. 14.3% of them had serious depressio n. After 6 weeks treatment of antidepressant, 68.9% were cured, 27.8% improved d ramatically, 1.64% improved, the other 1.64% made no improvement. (paired t-test , p＜0.01) Conclusion: Antidepressant can improve depression of patients in general hospital, so that decrease the probability of over-examinati on and inappropriate medical therapy.
【Key Words】depression antidepressant general hospital
目录：
一、一般资料
二、临床特点
三、HAMD治疗前后评分及临床疗效
四、副作用：
参考文献：
1，Richelson E，Treatment of acute depression.Psychiatry Clin North Am.1 993;16:461-478
2，张震.躯体疾病背景下的抑郁.中国心理卫生杂志，1993；(4)：167
3，萧世富等.世界卫生组织初级保健病人心理障碍合作研究的上海样本结果.中华精神科杂 志，1997；30(2)：90-94
4，蔡焯基等.抑郁症基础与临床，科学出版社 1997，176。
5，e Vane el.Pharmacokinetics of the newer antidepressants:Clinical relevance.A m J Med.1994;97(Suppl 6A):13-23.
6，Sartotius N,Ustun TB et al:In international study of psychological problems i n primary care:preliminary report from the W-H-O.Collaborative Project on Psycho logical Problem in General Health Care.Arch Gen Psychiatry 1993,50:819-824
资料包括： 论文(3页2302字)
说明：
【摘 要】 目的：探讨综合性医院抑郁障碍的临 床特点及治疗。方法：将各科以躯体不适就诊但经多方查治无效而转 来心理门诊的患者，进行汉密尔顿抑郁量表(HAMD)测评，HAMD≥18分者入组共70例，分别给 每日氟西汀20mg治疗6周，治疗前后查HAMD，并进行疗效评定。结果：70例 中，轻度、中度抑郁占85.7%，重度抑郁占14.3%。有71.49%的初诊患者的第一主诉是睡 眠 障碍和躯体不适。经服用抗抑郁剂氟西汀治疗六周后，HAMD评分结果明显下降(P＜0.01)， 痊愈率68.9%，显效率27.8%，进步1.64%，无效1.64%。治疗前后HAMD量表的五项因子评 分均有明显下降，具有显著意义(P＜0.01)。结论：综合医院抑郁障 碍患者及时识别、诊断，适当应用抗抑郁剂可有效缓解抑郁症状和躯体症状，减少不必要的 检查和治疗，利于患者疾病的康复。
关键词： 抑郁障碍,临床特点,抗抑郁治疗
Depression, Corresponding Treatment and Outcome in General Hos pital
【Abstract】Objective: To study depression, corresponding treatm ent and outcome in general hospital. Method: All patients referr ed to clinic of psychological co unsel were screened by HAMD, 70 of them scored higher than 18 were included. An t itdepressant (Flucidine 20 mg per day) was given for 6 weeks. Results: Among 70 p atients with depression, 71.5% consulted their physician with chief complaint of sleep disorder or somatic discomfort first. 14.3% of them had serious depressio n. After 6 weeks treatment of antidepressant, 68.9% were cured, 27.8% improved d ramatically, 1.64% improved, the other 1.64% made no improvement. (paired t-test , p＜0.01) Conclusion: Antidepressant can improve depression of patients in general hospital, so that decrease the probability of over-examinati on and inappropriate medical therapy.
【Key Words】depression antidepressant general hospital
目录：
一、一般资料
二、临床特点
三、HAMD治疗前后评分及临床疗效
四、副作用：
参考文献：
1，Richelson E，Treatment of acute depression.Psychiatry Clin North Am.1 993;16:461-478
2，张震.躯体疾病背景下的抑郁.中国心理卫生杂志，1993；(4)：167
3，萧世富等.世界卫生组织初级保健病人心理障碍合作研究的上海样本结果.中华精神科杂 志，1997；30(2)：90-94
4，蔡焯基等.抑郁症基础与临床，科学出版社 1997，176。
5，e Vane el.Pharmacokinetics of the newer antidepressants:Clinical relevance.A m J Med.1994;97(Suppl 6A):13-23.
6，Sartotius N,Ustun TB et al:In international study of psychological problems i n primary care:preliminary report from the W-H-O.Collaborative Project on Psycho logical Problem in General Health Care.Arch Gen Psychiatry 1993,50:819-824