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乳腺癌根治术后胸壁放疗技术与剂量分布

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摘要: 乳腺癌根治术后病人CT图像送入三维治疗计划系统,观察6 MV X线切线照射及电子线垂直照射胸壁时的剂量分布。包括内乳淋巴结和不包括内乳淋巴结的6 MV X线切线照射无需楔形板;单纯电子线垂直照射,即使是6 MeV低能电子线,肺组织受照亦相当严重;6 MeV电子线配合皮肤表面填0.5 cm厚组织等效物,肺组织受照较小,皮肤剂量提高,但内乳淋巴结与其表面皮肤剂量不能两者兼顾;9 MeV电子线配合皮肤表面填不等厚度组织等效物,可使得90%等效剂量包括皮肤、胸壁和内乳淋巴结而肺组织受照很少;对皮肤和内乳淋巴结均需高量照射者,电子线配合皮肤表面填组织等效物垂直照射较X线切线照射有明显优势。
  
关键词: 乳腺癌,根治术,放射治疗

Chest wall radiotherapy technique and dose distribution for patients of breast cancer after radical mastectomy
  
Abstract Sending the CT images of the patients of breast cancer after radical mastectomy to CADPLAN 3D TPS, studying the dose distribution of 6 MV X-ray tangential irradiation and different energy electron ray perpendicular irradiation to chest wall. Some results were presented. Including or not including the intramammary lymph. It is not necessary for 6 MV X beam tangential irradiation to chest wall of the patient of brest cancer after radical mastectomy. Perpendicular irradiation by 6 MV electron beam only the irradiation of the lung is serious and the dose of the skin is low. Perpendicular irradiation by 6 MV electron beam with 0.5 cm bolus as compensator, it can reduce the irradiation of the lung and make dose of the skin high but it will reduce the dose of intramammary lymph if above it the skin is overlaid of bolus. Perpendicular irradiation by 9 MeV electron beam with unequal thickness bolus overlaid on the skin,it can make 90% isdose line involving the skin chest and intramammary lymph but the lung which is irradiated is small. If both skin and intramammary lymph need high dose irradiation perpendicular irradiation by electron beam with bolus as compensator has the significant superiority than X beam tangential irradiation.
 
 Key words breast cancer; radical mastectomy; radiotherapy;dose distribution
目录:
1 材料和方法

  2 结 果

  3 讨 论

  4 结 论


参考文献:
 1,Harris JR,echt A Connolly Jet al.Conservative surgery and radiotherapy for early breast cancer[J]. Cancer1990,66:1427.
  2,Amalric R et al. Radiation therapy with or without primary limited surgery for operable breast cancer[J].Cancer,1982, 49(1):30.
  3,Montague ED. Conservation surgery and radiation therapy in the treatment of operable breast cancer[J]. Cancer,1984,53(3):700.
  4,Hellman S et al. Radiation therapy of early carcinoma of the breast without mastectomy[J]. Cancer,1980,46(4):988.
  5,胡逸民,等.乳腺癌水平切线技术及剂量计算方法.中国放射肿瘤学[J],1987,1(3):57.
  6,谷铣之,殷蔚伯,刘泰福等主编.肿瘤放射治疗学[M].北京,北京医科大学中国协和医科大学联合出版社.1997,807.
  7,Carlos A. Perez, Luther W. Brady. Principles and practice of radiation oncology[M]. 1987,753.


作者点评:
 根治术后胸壁放疗病人,6 MeV X线切线照射无需楔形板。单纯电子线垂直照射不足取。电子线照射配合组织补偿块的应用,有利于保护肺组织受照,减少放射性肺炎发生几率。对皮肤和内乳淋巴结均需高量照射者,电子线配合组织补偿块的应用,较X线切线照射有明显优势。
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