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资料包括： 论文(4页3968字)
说明：
关键词： 帕金森病,电刺激,丘脑,苍白球,底丘脑核
摘要：随着立体定向技术及电刺激装置的迅速发展，脑深部电刺激治疗帕金森病作为一种非破坏性的功能性治疗方法，在国外逐渐发展成熟，并被认为是目前最理想的治疗方法之一。本文就脑深部电刺激治疗帕金森病的现状作一简要综述。
Treatment for Parkinson’s disease with deep brain electrostimulation
Abstract：Along with the rapid devlopments of stereotactic operation and electrostimulation devices,the treatment for Parkinson’s disease with deep brain electrostimulation,as a sort of non_destructive functional cure,is becoming gradually mature abroad,and is regarded as the idealest therapy at present ,The status of treatment for Parkinson’s disease with deep brain electrostimulation was reviewed concisely here.
Key words：Parkinson’s disease;electrostimulation;thalamus;globus pallidus;subthalamic nucleus
目录：
1 电刺激术治疗帕金森病(PD)简史
2 刺激定位选择
3 刺激方法及参数
4 刺激的作用机理与效果
参考文献：
［1］Benabid AL.Long_term suppression of tremor by chronic stimula tion of the ventral intermediate thalamic nucleus[J].Lancet, 1991,337:403
［2］Bechereva NP.Method of eletrostimulation of the deep brain structure in treatment some chronic disease[J].Confin Neurol, 1975,37:136
［3］Brice J.Supprosion of intention tremor by contingent deep_brain stimulation [J］.Lancet,1980,1:1 221
［4］Ohye C,Hirai T,Miyazaki M,et al.VIM thalamotomy for the treatment varionskinds tremor[J].Applied.Neurophysiology, 1982,45:275
［5］Hirain T,Miyazaki M,Nakajma H,et al.The correlation between tremor characteristics and predicted volume of effective lesions in stereotaxic nu cleusventralisintermedius thalamotomy[J].Brain,1983,106:1 201
［6］Andy OJ.Thalamic stimulation for control of movement disordersby chronic tereotaxic stimulation of the ventral intermediate thalamic nucleus[J].JNeurosurg,1992,77:62
［7］Limousine P,Pollak P,Benazzouz A,et al.Improvement in parkinsonian symptoms after bilateral subthalamic nucleus stimulation[J].Lancet,1995,345:91
［8］Tronnier VM,Fogel W,Kronenbuercer M,et al.Pallidal stimulation:an al ternative to pallidotomy[J].J Neurosurg,1997,87:700
［9］Ghika J,Villermuer J,Fankhauser H,et al.Effeciency and safety of bilateral contemporaneous pallidal stimulation(deep brain stimulation) in levodopare sponsive patients with Parkinson’s disease with severe motor fluctuations:a 2－years follow－ up review[J].J Neurosurg,1998,89:713
［10］Blond S.Control of tremors and involuntary movement disorders by chronic stereotactic stimulation of the ventral interme diate thalamic nucleus[J].J Neurosurg,1992,77:62
［11］Iacono RP,Lonser RR,Maeda G,et al.Chronic anterior pallodal stimula tion for Parkinson’s disease[J].Acta Neurochirurgica, 1995,137:106
［12］Siegfried J,Lippita B.Bilateral chronic eletrostimulation of ventroposter plateral pallidum:a new therapeutic approach for alleviating all Parkinsinian symptoms[J].Neurosurgery,1994,35:1 126
［13］Limousine P,Pollak P,Benazzouz A,et al.Improvement in parkinsonian symptoms after bilateral subthalamic nucleus stimulation[J].Lancet,1995,345:91
［14］Deiber MP,Pollak P,Passingham R,et al.Thalamic stimulation and sup pression of parkinsonian tremor[J].Brain,1993,116:267
［15］Benabid AL,Pollak P,Gao D,et al.Chronic electrical stimulation of the VIM of the thalamus as a treatment of movement disorders[J].J Neurosug,1996,84:203
［16］Benabid AL,Pollak P,Gross C,et al.Acute and long_term effects of STN stimulation in PD[J].Stereotact Funct Neurosurg,1994,62:76
［17］Cooper IS.Chronic cerebellar stimulation and DBS in involuntary move ment disorders[J].Appl Neurphsiol,1982,45:209
［18］伦学庆，章翔，张延庆，等.高频电刺激丘脑底核治疗帕金森病的实验研究[J].中华老年医学杂志，1998，17(3)：146
