偏头痛的经颅多普勒超声研究概况
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资料包括： 论文(4页3797字)
说明：
关键词： 偏头痛,经颅多普勒超声,脑血流速度,脑血管反应性
偏头痛是神经系统常见疾病之一,其发病机理不详。1938年Graham等［1］提出偏头痛的血管学说,认为偏头痛是由于脑血管痉挛继发脑血管扩张引起的。虽然以后提出神经学说、体液学说及免疫学说等,但是最终均导致脑血管的异常舒缩反应引起头痛发作。有关偏头痛的脑血流动力学特征一直缺乏客观而实际可行的实验室指标,经颅多普勒超声的问世开创了非创伤性检测脑部血流动力学的新纪元,成为评价偏头痛脑血管功能状态的首选检查方法。
1842年,Christoan发现了著名的多普勒效应［2］,但直到1982年Aaslid等［3］才利用低频超声波的良好穿透能力,建立了经颅多普勒超声技术(transcranial doppler ultrosonography,TCD)。国内自1988年引进TCD技术以来发展迅速,在临床与科研方面做了大量工作,其中对偏头痛的观察研究即为其一。
1990年美国神经病学学会治疗学与技术评价小组［4］对TCD技术作了简要的临床评价,认为TCD对于揭示偏头痛时脑动脉的病理生理学改变很有前途。目前国内外广泛应用TCD技术检测偏头痛各期的脑血流动力学特征及脑血管的反应性,以推测脑血管的功能状态,为临床诊断治疗提供重要依据。
目录：
1 研 究 现 状
2 存在问题及展望
参考文献：
1 Graham J,wolff HG.Arch Neurol Psychiatry,1939,39:737.
2 焦明德主编.实用经颅多普勒超声学.北京:北京医科大学中国协和医科大学联合出版社,1995.2.
3 Aaslid R,Markwalder TM,Nornesive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries.J Neurosurg,1982,57:769-774.
4 The AmericanAcademy of Neurollgy,Assessment:transcranial Doppler.Neurology,1990,40:680.
5 Thie A,Spitzer k,Lachenmayer l,et al.Prolonged vasospsam in migraine detected by noninvasive transcranial Doppler ultrasound.Headache,1988,28:183-186.
6 Thie A,Fuhlendorf A,Spitzer K,et al.Transcranial Doppler evaluation of common and classic migraine.part I.Ultrasonic features during the headache free period.Headache,1990,30:201-208.
7 Abernathy M,Donnelly G,et al.Transcranial Doppler sonography in headache-free migraineurs.Headache,1994,34:198-203.
8 Valikovics A,Olah L,Fulesdi B,et al.Cerebrovascular reactivity messured by transcranial doppler in migraine.Headeche,1996,36:323-328.
9 宋鲁平,张秀敏,贾崇琪,等.TCD对普通和典型偏头痛患者间歇期血管机能状态的研究.临床神经病学杂志,1995,8:268-270.
10 Thie A,Fuhlendorf A,Spitzer K,et al.Transcranial Doppler evaluation of common and classic migraine.part Ⅱ.Ultrasonic features during attacks.Headache,1990,30:209-215.
11 Totaro R,De-Matteis G,Marini C,et al.Cerebral blood flow in migraine with aura:a transcranial Doppler songography study.Headache,1992,32:446-451.
12 Thomsen ll,Iversen HK,Olesen J.Cerbral blood flow velocities are reduced during attacks of unilateral migrine without aura.Cephalalgia,1995,15:109-116.
13 Friberg L.Olesen J,Iversen HK,et al.Migraing pain associated with middle cerebral artery dilatation:reversal by sumatriptan.Iancet,1991,338:13-16.
14 耿晓非,李晓井,刘培霞.典型偏头痛和普通型偏头痛TCD检查对照研究.中国超声医学杂志,1996,12:17-18.
15 La-Spina,Calloni MV,Porazzi D,Transcranial Doppler monitoring of a migraine with aura attack from the prodromal phase to the end.Headache,1994,34:593-596.
16 La-Spina,Vignati A,Porazzi D.Basilar artery migraine:transcranial Doppler EEG and SPECT form the aura phase to the end headache,1997,37:43-47
17 Thomas TD,Harpold GJ,Troost BT.Gerebrovascular reactivity in migraineurs as measured by transcranial Doppler.Cephalalgia,1990,10:95-99.
18 Harer C,von Kummer R.Cerebrovascular CO2 reactivith in migraine assessment by transcranial Doppler ultrasound.J-Neurol,1991,238:23-26.
19 Fiermonts G,Pierelli F,Pauri F,et al.Cerebro-vascular CO2 reactivity in migraine with aure and without aura.Atranscranial Doppler study.Acta-Neurol-Scand,1995,92:166-169.
20 Thie A,Carvajal-lizano M.Schlichting U,et al.Multimodal tests of cerebrovascular reactivity in migraine:a transcranial Doppler study.J-Neurol,1992,239:338-342.
21 Zanette EM,Agnoli A,Cerbo R,et al.Trans-cranial Doppler(TCD)arter nitroglycerin in migraine without aura.Headache,1991,39:596-598.
22 Thomsen LL,Iversen HK,Brinck TA,et al.Arterial supersensitivity to nitric oxide(nitroglycerin)in migraine sufferers.Cephalalgia,1993,13:395-399.
23 Silvestrini M,Matteis M,Troisi F,et al,Cerebrovascular reactivity in migraing with and without aura.Headache,1996,36:37-46.
24 贺茂林.经颅多普勒超声检测及临床应用.中国超声医学杂志,1994,10:48-50.
资料包括： 论文(4页3797字)
说明：
关键词： 偏头痛,经颅多普勒超声,脑血流速度,脑血管反应性
偏头痛是神经系统常见疾病之一,其发病机理不详。1938年Graham等［1］提出偏头痛的血管学说,认为偏头痛是由于脑血管痉挛继发脑血管扩张引起的。虽然以后提出神经学说、体液学说及免疫学说等,但是最终均导致脑血管的异常舒缩反应引起头痛发作。有关偏头痛的脑血流动力学特征一直缺乏客观而实际可行的实验室指标,经颅多普勒超声的问世开创了非创伤性检测脑部血流动力学的新纪元,成为评价偏头痛脑血管功能状态的首选检查方法。
1842年,Christoan发现了著名的多普勒效应［2］,但直到1982年Aaslid等［3］才利用低频超声波的良好穿透能力,建立了经颅多普勒超声技术(transcranial doppler ultrosonography,TCD)。国内自1988年引进TCD技术以来发展迅速,在临床与科研方面做了大量工作,其中对偏头痛的观察研究即为其一。
1990年美国神经病学学会治疗学与技术评价小组［4］对TCD技术作了简要的临床评价,认为TCD对于揭示偏头痛时脑动脉的病理生理学改变很有前途。目前国内外广泛应用TCD技术检测偏头痛各期的脑血流动力学特征及脑血管的反应性,以推测脑血管的功能状态,为临床诊断治疗提供重要依据。
目录：
1 研 究 现 状
2 存在问题及展望
参考文献：
1 Graham J,wolff HG.Arch Neurol Psychiatry,1939,39:737.
2 焦明德主编.实用经颅多普勒超声学.北京:北京医科大学中国协和医科大学联合出版社,1995.2.
3 Aaslid R,Markwalder TM,Nornesive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries.J Neurosurg,1982,57:769-774.
4 The AmericanAcademy of Neurollgy,Assessment:transcranial Doppler.Neurology,1990,40:680.
5 Thie A,Spitzer k,Lachenmayer l,et al.Prolonged vasospsam in migraine detected by noninvasive transcranial Doppler ultrasound.Headache,1988,28:183-186.
6 Thie A,Fuhlendorf A,Spitzer K,et al.Transcranial Doppler evaluation of common and classic migraine.part I.Ultrasonic features during the headache free period.Headache,1990,30:201-208.
7 Abernathy M,Donnelly G,et al.Transcranial Doppler sonography in headache-free migraineurs.Headache,1994,34:198-203.
8 Valikovics A,Olah L,Fulesdi B,et al.Cerebrovascular reactivity messured by transcranial doppler in migraine.Headeche,1996,36:323-328.
9 宋鲁平,张秀敏,贾崇琪,等.TCD对普通和典型偏头痛患者间歇期血管机能状态的研究.临床神经病学杂志,1995,8:268-270.
10 Thie A,Fuhlendorf A,Spitzer K,et al.Transcranial Doppler evaluation of common and classic migraine.part Ⅱ.Ultrasonic features during attacks.Headache,1990,30:209-215.
11 Totaro R,De-Matteis G,Marini C,et al.Cerebral blood flow in migraine with aura:a transcranial Doppler songography study.Headache,1992,32:446-451.
12 Thomsen ll,Iversen HK,Olesen J.Cerbral blood flow velocities are reduced during attacks of unilateral migrine without aura.Cephalalgia,1995,15:109-116.
13 Friberg L.Olesen J,Iversen HK,et al.Migraing pain associated with middle cerebral artery dilatation:reversal by sumatriptan.Iancet,1991,338:13-16.
14 耿晓非,李晓井,刘培霞.典型偏头痛和普通型偏头痛TCD检查对照研究.中国超声医学杂志,1996,12:17-18.
15 La-Spina,Calloni MV,Porazzi D,Transcranial Doppler monitoring of a migraine with aura attack from the prodromal phase to the end.Headache,1994,34:593-596.
16 La-Spina,Vignati A,Porazzi D.Basilar artery migraine:transcranial Doppler EEG and SPECT form the aura phase to the end headache,1997,37:43-47
17 Thomas TD,Harpold GJ,Troost BT.Gerebrovascular reactivity in migraineurs as measured by transcranial Doppler.Cephalalgia,1990,10:95-99.
18 Harer C,von Kummer R.Cerebrovascular CO2 reactivith in migraine assessment by transcranial Doppler ultrasound.J-Neurol,1991,238:23-26.
19 Fiermonts G,Pierelli F,Pauri F,et al.Cerebro-vascular CO2 reactivity in migraine with aure and without aura.Atranscranial Doppler study.Acta-Neurol-Scand,1995,92:166-169.
20 Thie A,Carvajal-lizano M.Schlichting U,et al.Multimodal tests of cerebrovascular reactivity in migraine:a transcranial Doppler study.J-Neurol,1992,239:338-342.
21 Zanette EM,Agnoli A,Cerbo R,et al.Trans-cranial Doppler(TCD)arter nitroglycerin in migraine without aura.Headache,1991,39:596-598.
22 Thomsen LL,Iversen HK,Brinck TA,et al.Arterial supersensitivity to nitric oxide(nitroglycerin)in migraine sufferers.Cephalalgia,1993,13:395-399.
23 Silvestrini M,Matteis M,Troisi F,et al,Cerebrovascular reactivity in migraing with and without aura.Headache,1996,36:37-46.
24 贺茂林.经颅多普勒超声检测及临床应用.中国超声医学杂志,1994,10:48-50.