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【摘要】 目的 探讨孕产妇输血传播病毒（TTV）感染率及其在母婴间的传播途径。方法 应用巢式聚合酶链反应（n-PCR）技术检测60例健康孕产妇(观察组)静脉血TTV，并对TTV阳性产妇的乳汁及其新生儿脐血进行检测。并以251例健康非孕妇女(对照组)的TTV感染情况作对照。 结果 观察组TTV感染率为28.33 %，对照组TTV感染率为7.57%，两组比较差异有非常显著性（P＜0.001）。观察组中TTV阳性产妇乳汁TTV检出率为27.27%，其新生儿脐血未检出TTV。结论 孕产妇TTV感染率较高，TTV可能通过乳汁感染新生儿，但母婴间不存在垂直传播关系。
关键词： 肝炎病毒,聚合酶链反应,疾病传播,垂直
A Clinical Prospective Study on Maternal-fetal Transfusion Transmitted Virus Infection
【Abstract】 Objective To observe the transfusion transmitted virus (TTV) infection rate in gravidas and parturients，and explore the route of maternal-fetal transmission. Methods TTV infection was detected by nest-polymerase chain reaction (n-PCR) in the serum of 60 healthy gravidas and parturientes. Once parturient infection was identified, the latices and the umbilical blood were examined for TTV infection as well. Meanwhile, a group of non-pregnant healthy women was tested as control. Results The infection rate of observation group was 28.33%, while in the control group it was 7.57%. The difference of the two groups was significant (P＜0.001). Of the TTV positive parturientes, TTV infection rate of their latices was 27.27%, but none of the umbilical blood samples showed TTV positive. Conclusions The TTV infection rate of gravidas and parturientes is higher than that of non-pregnant healthy women. TTV can infect newborns through latices, however, there is no vertical maternal-fetal transmission.
【Key words】 Hepatitis viruses; Polymerase chain reaction; Disease transmisson, vertical
目录：
一、 研究对象
二、 方法
三、统计学方法
参考文献：
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