【网学提醒】：本文主要为网上学习者提供无支架生物二尖瓣的进展，希望对需要无支架生物二尖瓣的进展网友有所帮助，学习一下吧!
资料包括： 论文(4页3451字)
说明：
关键词： 无支架生物二尖瓣,二尖瓣替换
中国协和医科大学 心血管研究所 阜外心血管病医院 * 博士生 传统支架生物瓣设计与天然心脏瓣膜相差很大，由于瓣架的存在造成应力的集中，易导致瓣叶撕裂，二尖瓣失功〔1，2〕。传统生物瓣替换需要在二尖瓣环处植入硬环，术中不保留二尖瓣瓣下结构的完整性，这些都可影响术后效果和左心室功能。为了避免支架生物瓣的缺点，使生物二尖瓣更加符合生理要求，加之近年来对二尖瓣装置生理功能认识的深入，无支架生物二尖瓣再度受到重视。现就这方面的一些进展作一综述。
无支架生物二尖瓣的种类
根据无支架生物二尖瓣材料的构成可分为以下几类：
1.同种瓣：包括同种二尖瓣、主动脉瓣、肺动脉瓣。早在60年代就已开始同种二尖瓣替换的研究，由于当时手术方法和组织保存等限制，结果不很满意〔3〕。最近Acar等〔4〕报告43例病人接受超低温保存同种二尖瓣替换手术，其中21例为部分瓣膜替换，22例为全瓣膜替换，术后效果良好。随访14个月，超声心动图检查20例无二尖瓣反流，13例轻度反流，5例中度反流；瓣口面积：部分瓣膜替换为2.5±0.4cm2，全瓣膜替换为2.7±0.4cm2，跨瓣压3±4mmHg(1mmHg=0.133kPa)。
目录：
1.同种瓣
2.异种瓣即猪二尖瓣
3.牛心包和自体心包二尖瓣
4.利用生物组织工程制作的瓣膜
参考文献：
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